Work

Enhanced cleavage of APP by co-expressed Bace1 alters the distribution of APP and its fragments in neuronal and non-neuronal cells

Year: 2022

Type: article

Source: Molecular Neurobiology

DOI: 10.1007/s12035-022-02733-6

Authors: Jonathan Aow, Tzu-Rung Huang, Gopal Thinakaran, Edward H. Koo

Institutions: Agency for Science, Technology and Research, National University of Singapore, Genome Institute of Singapore, University of South Florida, USF Health Byrd Alzheimer's Institute, University of California San Diego

Language: English

Topic: Alzheimer's disease research and treatments

Subfield: Physiology (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Research Foundation Singapore, National Institutes of Health, National Institute on Aging, National Institute of Neurological Disorders and Stroke

Awards: G128085619, G2350003632, Mechanisms of abeta induced dysfunction in hippocampal neuronal circuitry, Cell autonomous and non-cell autonomous roles of the GWAS risk factor BIN1 in Alzheimer's disease neuropathology, Regulation of BACE1 transcytosis in hippocampal neurons, The role of elevated BIN1 expression in Alzheimer's disease

OpenAlex ID: W4221057526

FWCI: 1.358

Cites: 44

Cited by: 10

Related to: 10