Work

Tuberculosis vaccines in the era of Covid-19 – what is taking us so long?

Year: 2022

Type: review

Abstract: The Mycobacterium bovis BCG vaccine was first used in 1921, but has not controlled the global spread of tuberculosis (TB). There are still no new licensed tuberculosis vaccines, although there much active research and a vaccine development pipeline, with vaccines designed to prevent infection, prevent disease, or accelerate TB treatment. These vaccines are of different types, and designed to replace BCG, or to boost immunity following BCG vaccination. This viewpoint discusses why, when it has been possible to develop new vaccines for SARS-CoV-2 so quickly, it is taking so long to develop new tuberculosis vaccines.

Source: EBioMedicine

DOI: 10.1016/j.ebiom.2022.103993

Authors: Hazel M. Dockrell, Helen McShane

Institutions: London School of Hygiene & Tropical Medicine, University of Oxford, Jenner Institute

Language: English

Topic: Tuberculosis Research and Epidemiology

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,500