Work

Generation of formaldehyde and formaldehyde-d 2 for hydroxymethylations and hydroxydeuteromethylations of difluoroenolates and difluorobenzyl carbanions

Year: 2022

Type: article

Abstract: for the production of 2,2-difluoro-1,1-deuteroethanols. Mechanistic and computational studies further characterize the production of hydroxymethylated and hydroxydeuteromethylated difluorinated organic molecules.

Source: Chemical Communications

DOI: 10.1039/d2cc01518h

Authors: Hari R. Khatri, Changho Han, Reem A. Alkhodier, Amna T. Adam, Baharul Islam, David A. Colby

Institutions: University of Mississippi, Purdue University West Lafayette

Language: English

Topic: Fluorine in Organic Chemistry

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

Open Access status: green

Funders: National Institute on Drug Abuse, National Institute of General Medical Sciences

Awards: Center of Research Excellence in Natural Products Neuroscience (CORE-NPN), Developing Biased Agonists of the GABA-B Receptor, GlyCORE: Glycoscience Center of Research Excellence

OpenAlex ID: W4223507003

FWCI: 0.31

Cites: 32

Cited by: 5

Related to: 10