Work

The Role of Tissue Biopsy in the Management of Immune Checkpoint Inhibitor Toxicity

Year: 2022

Type: article

Abstract: Immune checkpoint inhibitors have revolutionized the treatment of cancer and are now omnipresent. However, immune-related adverse events can present with varying phenotypes and timing, which can pose diagnostic and therapeutic challenges for the treating oncologist as well as subspecialty consultants. Biopsies of affected organs may provide insight into biologic mechanisms as well as potentially guide management in certain circumstances.

Source: Journal of the National Comprehensive Cancer Network

DOI: 10.6004/jnccn.2022.7011

Authors: Leslie A. Fecher, Shrinivas Bishu, Robert J. Fontana, Salim S. Hayek, Bryan J. Schneider

Institution: University of Michigan

Language: English

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Bristol-Myers Squibb, Pfizer, EMD Serono, National Heart, Lung, and Blood Institute