Work

How Image-Guided Pathology Can Improve the Detection of Lymph Node Metastases in Prostate Cancer

Year: 2022

Type: article

Abstract: ABSTRACT: Detection of lymph node (LN) metastases in prostate cancer (PCa) is pivotal for accurate staging and determining treatment options. To date, the reference standard for nodal staging is histopathological examination of all harvested surgical specimens from extended pelvic LN dissections. However, this is a labor-intensive process, and small metastatic foci can be missed due to sampling effects. With current research expanding toward using radiolabeled prostate-specific membrane antigen ligands for image-guided surgery, new opportunities arise for image-guided pathological assessment of surgical specimens. Here, we illustrate how molecular imaging can complement histopathology and improve accurate detection of LN metastases.

Source: Clinical Nuclear Medicine

DOI: 10.1097/rlu.0000000000004158

Authors: Melline G.M. Schilham, Heidi Küsters-Vandevelde, Diederik M. Somford, M. Rijpkema, Martin Gotthardt

Institutions: Radboud University Medical Center, Prosper Hospital, Canisius-Wilhelmina Ziekenhuis

Language: English

Topic: Prostate Cancer Diagnosis and Treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4224233539

FWCI: 0.484

Cites: 8

Cited by: 3

Related to: 10