Work

Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemia

Year: 2022

Type: article

Source: Cancer Cell

DOI: 10.1016/j.ccell.2022.04.001

Authors: Mark B. Leick, Harrison Silva, Irene Scarfò, Rebecca Larson, Bryan D. Choi, Amanda A. Bouffard, Kathleen Gallagher, Andrea Schmidts, Stefanie R. Bailey, Michael C. Kann, Max Jan, Marc Wehrli, Korneel Grauwet, Nora Horick, Matthew J. Frigault, Marcela V. Maus

Institutions: Harvard University, Massachusetts General Hospital

Language: English

Topic: CAR-T cell therapy research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Cancer Institute, National Institute of Allergy and Infectious Diseases

Awards: Training in Transplantation Biology, Efficacy and immune effects of anakinra prophylaxis for neurologic toxicity and cytokine release syndrome in patients with lymphoma receiving axicabtagene ciloleucel, Molecular Immunology and Tumor Biology, Novel CAR T cell engineering strategies for effective eradication of solid and liquid tumors, Training Program in Cancer Biology and Therapeutics, Understanding and manipulating programmed cell death (PCD) pathways to facilitate lymphoid tumor killing by CAR T cells

OpenAlex ID: W4224244393

FWCI: 12.33

Cites: 81

Cited by: 137

Related to: 10