Work

Tetrahydroxydiboron‐Mediated Palladium‐Catalyzed Deoxygenative Transfer Hydrogenation of Aryl Ketones

Year: 2022

Type: article

Abstract: We describe a palladium‐catalyzed deoxygenative transfer hydrogenation of ketones using B 2 (OH) 4 as the sole additive. Deuterium labeling experiments using B 2 (OD) 4 show that the incorporated protons originate exclusively from the diboron reagent. Spectroscopic evidence implicates the intermediacy of a borate ester. A variety of aromatic ketones can be deoxygenated using this approach. magnified image

Source: Advanced Synthesis & Catalysis

DOI: 10.1002/adsc.202200482

Authors: William C. Spaller, Jennifer Q. Lu, Benjamin J. Stokes

Institutions: University of California, Merced, Santa Clara University

Language: English

Topic: Asymmetric Hydrogenation and Catalysis

Subfield: Inorganic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: National Aeronautics and Space Administration

Award: G5085487510