Year: 2022
Type: article
Abstract: As part of the 2021 Immunotherapy Bridge virtual congress (December 1-2, Naples, Italy), the Great Debate sessions featured experts who were assigned counter opposing views on four important questions in immunotherapy today. The first topic was whether oncolytic viruses or other specific immunomodulators were the more promising approach for intralesional therapy. The second was whether early surrogate endpoints, such as response rate or progression-free survival, correlate with long-term overall survival was considered. Thirdly, whether vaccines can transform cold into hot tumors was discussed and, finally, broad versus deep analytic profiling approaches to gain insights into immune-oncology development were compared. As with previous Bridge congresses, presenters were invited by the meeting Chairs and positions taken during the debates may not have reflected their respective personal view. In addition, the views summarised in this article are based on available evidence but may reflect personal interpretation of these data, clinical experience and subjective opinion of the speaker.
Institutions: Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", University of California, San Francisco, Parker Institute for Cancer Immunotherapy, University of Pittsburgh, The University of Texas MD Anderson Cancer Center, Angeles Clinic and Research Institute, Memorial Sloan Kettering Cancer Center, Roswell Park Comprehensive Cancer Center, Northwestern University, Providence Portland Medical Center, Moffitt Cancer Center
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,190
Funder: National Cancer Institute
OpenAlex ID: W4224246779