Work

Possible Mechanism of SARS-CoV-2 Nsp1-Mediated Control of Viral Gene Expression

Year: 2022

Type: article

Abstract: The relation between the structures of Nsp1 proteins and their function is further revealed.• The molecular mechanism of viral mRNA escape from Nsp1 suppression is developed and interpreted.• The Nsp1 has no effect on viral proteins, which is helpful to gain insights into SARS-CoV-2 infection and to understand the impacts of protein structure in the context of replication.

Source: Frontiers in Cellular and Infection Microbiology

DOI: 10.3389/fcimb.2022.881749

Authors: Tie Zhao, Yi Ren, Jianguo Wu, Qiwei Zhang

Institutions: Jinan University, University of South China, Southern Medical University

Language: English

Topic: SARS-CoV-2 and COVID-19 Research

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,950