Work

Discovery of First-in-Class TAK1–MKK3 Protein–Protein Interaction (PPI) Inhibitor (R)-STU104 for the Treatment of Ulcerative Colitis through Modulating TNF-α Production

Year: 2022

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.1c02198

Authors: Mei-Lin Tang, Haidong Li, Jin-Feng Ning, Xiaoyan Shen, Xun Sun

Institution: Fudan University

Language: English

Topic: Inflammatory Bowel Disease

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Science and Technology Commission of Shanghai Municipality, Shanghai Municipal Commission of Economy and Informatization

Awards: G4700040049, G5547462792, G6614664605, G7629759311

OpenAlex ID: W4224270484

FWCI: 1.508

Cites: 76

Cited by: 13

Related to: 10