Work

Materials-driven approaches to understand extrinsic drug resistance in cancer

Year: 2022

Type: review

Abstract: intrinsic cell genetics in determining drug response. Sophisticated systems biology tools that can de-convolve a crowded network of signals and responses, as well as controllable microenvironments capable of providing discrete and tunable extracellular cues can help us begin to interrogate the high dimensional interactions governing drug resistance in patients.

Source: Soft Matter

DOI: 10.1039/d2sm00071g

Authors: Justin R. Pritchard, Michael J. Lee, Shelly R. Peyton

Institutions: Pennsylvania State University, University of Massachusetts Chan Medical School, University of Massachusetts Amherst

Language: English

Topic: Cancer Cells and Metastasis

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Jayne Koskinas Ted Giovanis Foundation for Health and Policy, National Institutes of Health, National Cancer Institute, National Institute of Biomedical Imaging and Bioengineering