Work

Association between cardiorespiratory fitness and cerebrovascular reactivity to a breath-hold stimulus in older adults: influence of aerobic exercise training

Year: 2022

Type: article

Study design: Observational Study

Abstract: Earlier studies evaluating associations between cardiorespiratory fitness (CRF) and cerebrovascular reactivity (CVR) have demonstrated conflicting findings dependent on imaging modality or subject characteristics in individuals across a narrow range of CRF. This study demonstrates that CRF is nonlinearly associated with CVR measured by blood oxygen level dependent (BOLD) fMRI in a large sample of middle-aged and older adults across a wide range of CRF, suggesting that conflicting prior findings are related to the range of CRFs studied.

Source: Journal of Applied Physiology

DOI: 10.1152/japplphysiol.00599.2021

Authors: Lyndsey E. DuBose, Timothy B. Weng, Gary L. Pierce, Conner Wharff, Lauren Reist, Chase Hamilton, Abby O’Deen, Kaitlyn Dubishar, Abbi Lane-Cordova, Michelle W. Voss

Institution: University of Iowa

Language: English

Topic: Cardiovascular and exercise physiology

Subfield: Complementary and alternative medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute on Aging, NIH Office of the Director, National Center for Research Resources, National Center for Advancing Translational Sciences

Awards: University of Iowa - Research 3T MRI Connectome Upgrade, University of Iowa Clinical and Translational Science Program (KL2), University of Iowa Institute for Clinical and Translational Science, G240952461, Targeting Inflammation to Treat Cardiovascular Aging in Humans, Exercise to improve hippocampal connectivity and learning in older adults, Ovarian Hormone Regulation of Central and Cerebrovascular Hemodynamics, Integrative Physiology of Aging Training Grant

OpenAlex ID: W4224990284

FWCI: 3.243

Cites: 70

Cited by: 17

Related to: 10