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The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer

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Year: 2021
Type: article
Source: Molecular Cell
DOI: 10.1016/j.molcel.2021.11.014
Authors: Johannes Rudolph, Uma M. Muthurajan, Megan Palacio, Jyothi Mahadevan, Genevieve Roberts, Annette H. Erbse, Pamela N. Dyer, Karolin Luger
Institutions: University of Colorado Boulder, Howard Hughes Medical Institute
Language: English

Topic: DNA Repair Mechanisms
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences

Open Access status: bronze

Funders: Howard Hughes Medical Institute, American Heart Association, National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences
Awards: G1144445714, Investigating the role of PARP inhibitors in the treatment of DNA damage-induced cardiovascular pathologies, G5922074933, Predoctoral Training in Signaling and Cellular Regulation
OpenAlex ID: W4226058045
FWCI: 3.951
Cites: 93
Cited by: 85
Related to: 10
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