Work

Sulfane Sulfur Posttranslationally Modifies the Global Regulator AdpA to Influence Actinorhodin Production and Morphological Differentiation of Streptomyces coelicolor

Year: 2022

Type: article

Abstract: , this mechanism may represent a common regulating pattern of all AdpA-controlled biosynthetic pathways. Thus, this finding provides a new strategy for mining and activating valuable biosynthetic gene clusters.

Source: mBio

DOI: 10.1128/mbio.03862-21

Authors: Ting Lu, Xiaohua Wu, Qun Cao, Yongzhen Xia, Luying Xun, Huaiwei Liu

Institutions: Shandong University, State Key Laboratory of Microbial Technology, Washington State University

Language: English

Topic: Microbial Natural Products and Biosynthesis

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $3,900

Funders: National Natural Science Foundation of China, National Key Research and Development Program of China

Awards: G5499575918, G8982582370

OpenAlex ID: W4226291699

FWCI: 2.842

Cites: 63

Cited by: 24

Related to: 10