Work

Combined therapy with cisplatin and 5-AZA-2CdR modifies methylation and expression of DNA repair genes in oral squamous cell carcinoma.

Year: 2022

Type: article

Abstract: value CDDP increased expression of MLH1 in SCC-9. The data presented suggest that epigenetic drugs associated with chemotherapy have clinical translational potential as a therapy strategy to avoid or reverse cancer resistance, requiring further investigation.

Source: PubMed

Authors: Dieila Giomo Lima, Guilherme Castro Lima Silva do Amaral, Aline Cristiane Planello, Gabriell Bonifacio Borgato, Gustavo Narvaes Guimarães, Ana Paula de Souza

Institution: Universidade Estadual de Campinas (UNICAMP)

Language: English

Topic: Epigenetics and DNA Methylation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4226369930

FWCI: 0.657

Cites: 79

Cited by: 11

Related to: 10