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The AppNL-G-F mouse model of Alzheimer’s disease is refractory to regulatory T cell treatment

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Year: 2022
Type: preprint
Source: Research Square
DOI: 10.21203/rs.3.rs-1443371/v1
Authors: Lidia YSHII, Loriana Mascali, Lubna Kouser, Pierre Lemaitre, Marika Marino, James Dooley, Oliver Burton, Jeason Haughton, Zsuzsanna Callaerts-Vegh, Bart de Strooper, Matthew G Holt, Emanuela Pasciuto, Adrian Liston
Institutions: KU Leuven, Babraham Institute
Language: English

Topic: Alzheimer's disease research and treatments
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: green

Funders: Alzheimer's Association, Fonds Wetenschappelijk Onderzoek, Directorate for Biological Sciences, Biotechnology and Biological Sciences Research Council
Awards: G1990583613, G546953014, Develop a mechanistic understanding of how transcriptional and posttranscriptional regulation of gene expression is coordinated by signal transduction pathways., G6160911136, Use of an AAV9-based system for vectored immunoprophylaxis (VIP) targeting SOD1 in amyotrophic lateral sclerosis (ALS)., Immune homeostasis and the immune response, G8677781744
OpenAlex ID: W4226490962
Cites: 26
Cited by: 1
Related to: 10
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