Review 1: "Epistasis at the SARS-CoV-2 RBD Interface and the Propitiously Boring Implications for Vaccine Escape"
Year: 2022
Type: peer-review
Abstract: Rochman and colleagues perform an in silico mutagenesis experiment to evaluate the single point mutant landscapes for SARS-CoV-2 RBD from three different variants ("WT" -Wuhan Hu-1, Delta, Gamma) against binding to human ACE2 and a neutralizing antibody (nAb) CV30.Epistasis, as determined by non-linear mutational
Authors: Timothy Whitehead, Irene Francino-Urdaniz
Institution: University of Colorado Boulder
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4229015775