Work

Editor's evaluation: Cross-species analysis of LZTR1 loss-of-function mutants demonstrates dependency to RIT1 orthologs

Year: 2022

Type: peer-review

Abstract: Biochemical and genetic analysis of the functional relationship between RIT1 and its regulatory protein, LZTR1, across various model organisms helps define the substrate specificity of LZTR1 for RAS GTPases.

DOI: 10.7554/elife.76495.sa0

Author: Alice Berger

Institution: Fred Hutch Cancer Center

Language: English

Topic: Protein Kinase Regulation and GTPase Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

OpenAlex ID: W4229048549

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