Work

Metal-chelating benzothiazole multifunctional compounds for the modulation and 64 Cu PET imaging of Aβ aggregation

Year: 2020

Type: article

Abstract: A series of multifunctional compounds and their 64 Cu complexes exhibit good affinity for Aβ aggregates and can also control Aβ toxicity.

Source: Chemical Science

DOI: 10.1039/d0sc02641g

Authors: Yiran Huang, Hong-Jun Cho, Nilantha Bandara, Liang Sun, Diana Tran, Buck E. Rogers, Liviu M. Mirica

Institutions: University of Illinois Urbana-Champaign, Washington University in St. Louis, Hope Center for Neurological Disorders

Language: English

Topic: Alzheimer's disease research and treatments

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: Alzheimer's Association, National Institutes of Health, Charles F. and Joanne Knight Alzheimer Disease Research Center, Washington University in St. Louis, National Institute on Aging, National Institute of General Medical Sciences

Awards: Novel Bifunctional Chemical Agents as Theranostic Tools for Amyloid Diseases, G6310240282, G6808464556, Alzheimer's Disease Research Center

OpenAlex ID: W3041945825

FWCI: 5.715

Cites: 66

Cited by: 59

Related to: 10