Work

Methodological Issues in Clinical Drug Development for Essential Tremor

Year: 2012

Type: article

Abstract: Essential tremor (ET) is one of the most common tremor disorders in the world. Despite this, only two medications have received Level A recommendations from the American Academy of Neurology to treat it (primidone and propranolol). Even though these medications provide relief to a large group of ET patients, up to 50% of patients are non-responders. Additional medications to treat ET are needed. This review discusses some of the methodological issues that should be addressed for quality clinical drug development in ET.

Source: Tremor and Other Hyperkinetic Movements

DOI: 10.5334/tohm.116

Authors: Michael A. Carranza, Madeline R. Snyder, Rodger J. Elble, Angelique E. Boutzoukas, Theresa A. Zesiewicz

Institutions: University of South Florida, SIU Medicine

Language: English

Topic: Neurological disorders and treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $800