Work

Apoptin Studies Illuminate Intersection Between Lipidomics and Tumor Suppressors

Year: 2006

Type: article

Abstract: Improvements in current cancer treatment strategies have resulted in an increase in patient survival. Nevertheless, cancer remains a leading cause of death in the United States, and most cancer patients relapse and are resistant to subsequent treatments. Therefore, there is an urgent need for new treatment strategies and testing of novel therapeutic agents. Gene therapy is a promising strategy to treat malignancy. In the December 2006 issue of Molecular Therapy, Liu et al. evaluated the effects on tumors of delivery of the apoptin gene and uncovered an intersection between cancer gene therapy and bioactive lipid metabolism.

Source: Molecular Therapy

DOI: 10.1038/sj.jid.6300055

Authors: Sunil Chada, Rajagopal Ramesh

Institution: The University of Texas MD Anderson Cancer Center

Language: English

Topic: Virus-based gene therapy research

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,500