Work

Author response: CRISPR/Cas9 and active genetics-based trans-species replacement of the endogenous Drosophila kni-L2 CRM reveals unexpected complexity

Year: 2017

Type: peer-review

Abstract: Dissection of a cis-regulatory element (CRM) in its native chromosomal context using CRISPR/Cas9 editing and novel 'Active Genetics' reveals new features of CRM function and insights into how such regulatory elements change during evolution.

DOI: 10.7554/elife.30281.021

Authors: Xiang-Ru Shannon Xu, Valentino Matteo Gantz, Natalia Siomava, Ethan Bier

Institutions: University of California San Diego, University of Göttingen

Language: English

Topic: Genomics and Chromatin Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

OpenAlex ID: W4232356226

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