Work

Self-assembling peptides to mitigate familial hypercholesterolemia

Year: 2020

Type: other

Abstract: Elevated levels of low-density lipoprotein cholesterol (LDL-C) is one of the major contributors to ischemic cardiovascular disease (CVD), the leading cause of death in the United States and globally. PCSK9, a secretory mammalian serine protease, interacts with low-density lipoprotein receptors (LDLR) on the surface of hepatocytes, leading to the receptor’s internalization and

DOI: 10.1021/scimeetings.0c06690

Authors: Sreya Sanyal, Zain Siddiqui, Victoria Harbour, Ka Kyung Kim, Vivek Kumar, Biplab Sarkar

Language: English

Topic: Lipoproteins and Cardiovascular Health

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4233786661

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