Work

Abstract 1881: Hypoxia Inducible Factor (HIF) promotes reductive carboxylation by regulating citrate levels and renders VHL-deficient and hypoxic cells sensitive to glutamine deprivation.

Year: 2013

Type: conference-abstract

Source: Cancer Research

DOI: 10.1158/1538-7445.am2013-1881

Authors: Paulo Gameiro, Ana Metelo, Rocio Pérez-Carro, Alexandra Arreolla, Rania Baker, Zongwei Wang, Aria Olumi, Kimryn Rathmell, Pilar López-Larrubia, Gregory Stephanopoulos, Othon Iliopoulos

Institutions: Massachusetts General Hospital, Instituto de Investigaciones Biomédicas Sols-Morreale, University of North Carolina at Chapel Hill, UNC Lineberger Comprehensive Cancer Center, Massachusetts Institute of Technology

Language: English

Topic: Cancer, Hypoxia, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4233927598

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