Sulfamate esters guide C(3)–H functionalization of alkanes
Year: 2020
Type: other
Abstract: Owing to the pervasiveness of hydroxyl groups in natural isolates, alcohol derivatives are alluring directing groups. Herein, an alcohol-anchored sulfamate ester guides the xanthylation and alkylation of aliphatic C(3)–H bonds. The disclosed methods rely on light and photoredox mediated processes to generate sulfamyl radicals. These sulfamyl radicals template, otherwise rare,
Authors: Suraj K Ayer, Jennifer L Roizen
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: gold
OpenAlex ID: W4234412804