The Genome of Shope Fibroma Virus, a Tumorigenic Poxvirus, Contains a Growth Factor Gene with Sequence Similarity to those Encoding Epidermal Growth Factor and Transforming Growth Factor Alpha
Year: 1987
Type: article
Abstract: Degenerate oligonucleotide probes corresponding to a highly conserved region common to epidermal growth factor, transforming growth factor alpha, and vaccinia growth factor were used to identify a novel growth factor gene in the Shope fibroma virus genome. Sequence analysis indicates that the Shope fibroma growth factor is a distinct new member of this family of growth factors.
Source: Molecular and Cellular Biology
DOI: 10.1128/mcb.7.1.535
Authors: W Chang, C Upton, S L Hu, A F Purchio, G McFadden
Institutions: University of Washington, University of Alberta
Language: English
Subfield: Virology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W1811411196