Year: 2018
Type: conference-abstract
Abstract: Results: In vivo corneal epithelium, Bowman's layer, sub-basal nerve plexus (SNP), anterior, middle and posterior stromal keratocytes, stromal nerves, endothelial cells with nuclei were visualized with 1.3 mm x 1.3 mm field-of-view using FFOCT.Nuclei had an oval shape, which was becoming more oblong with depth.Thicknesses of the SNP and stromal nerves were measured to be 4 Æ 2 lm and 7 Æ 2 lm, respectively.Endothelial cells had diameters of 20 Æ 1 lm with their nuclei being 3.5 Æ 1 lm.Cells were hexagonal in shape with a round nuclei.The above results are in agreement with the known confocal microscopy data.Conclusions: FFOCT is a novel tool for non-contact imaging of millimeter sections of the in vivo human cornea with cellular resolution.Dimensions and shapes of the structures observed in FFOCT are in agreement with those seen in the conventional contact confocal microscopy.
Source: Acta Ophthalmologica
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W4234881940