Year: 2006
Type: article
Abstract: The Alzheimer's Disease Centers (ADC) Clinical Task Force developed the content of the UDS to be used by all ADCs (N ∼ 32) to establish a standardized examination and data collection protocol. NACC developed this content into case report forms and a computerized database management system. The NACC system was constructed to interface with all ADCs through user friendly, encrypted, web–based access. To describe the National Alzheimer's Coordinating Center (NACC) [U01 AG016976] Uniform Data Set (UDS) database, data submission system, and data dissemination methods. A Sunfire 880 server, using ORACLE and SAS software, houses the NACC UDS database; the NACC website (https://www.alz.washington.edu) was built using SAS and html. The web–based data submission system allows for individual subject web data entry or editing, as well as automatic, “batch” file uploading. Extensive range and logical error checking was included to insure “error free” data. Data are initially entered into the Working database where all errors and questionable data must be reconciled before data are sent to the Current database; periodically frozen copies of the Current database are made for research. The case report forms were designed at NACC and version control was built into the database to easily accommodate future changes. The database includes an automated data element dictionary to update data definitions and to provide automated documentation for the users. Data may be downloaded from the NACC database to an ADC user's local computer in a variety of formats. Extensive documentation for access and use of the database and data submission system is available on the NACC website. NACC also conducted a training session for all centers. Implementation of the system began in September 2005 across all ADCs. Clinical and Data Manager training sessions have been conducted. Data submission has recently begun. The NACC database and data submission system has been developed and is now operational. The 32 ADCs are submitting and storing UDS data to the NACC Database. Data can be accessed at https://www.alz.washington.edu.
Source: Alzheimer s & Dementia
Institutions: University of Washington, Washington University in St. Louis
Language: English
Subfield: Health Information Management
Field: Health Professions
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4235109945