Year: 1997
Type: article
Abstract: Acommon strategy for cancer gene therpy involves the transduction of a suicide gene such as the Herpes S正 mplex V 至 rus thymid 工 ne kiIlase ( HSVtk)gene followed by systemic administration Qf ganciclovir ( GCV ) ， This gene product phosphorylates GCV leadi to direct cytotoxicity ヒ hrough tern 正 1nation Qf DNA synthesis as well as indirect cell killing via the bystander effect ． ( F｛irpose ) In th正 s paper ， we describe the effectivness of adenoviral mediated
Source: The Japanese Journal of Urology
Author: Tayyaba Hasan
Institution: Massachusetts General Hospital
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W4235196299