Functional Genome-wide Screen Identifies Pathways Restricting Central Nervous System Axonal Regeneration
Year: 2018
Type: article
Abstract: (Cell Reports 23, 415–428; April 10, 2018) In the originally published version of this article, the legend for Figure 6G reads, “Scale bars represent 500 μm.” The correct legend for Figure 6G should read, “Scale bars represent 1,000 μm.” The authors regret this error. Functional Genome-wide Screen Identifies Pathways Restricting Central Nervous System Axonal RegenerationSekine et al.Cell ReportsApril 10, 2018In BriefSekine et al. conduct a genome-wide loss-of-function screen for factors limiting the success of CNS axonal regeneration in mice. They uncover a role for transport, receptor binding, and cytokine signaling pathways. In particular, in vivo loss of Rab27b expression increases axonal regeneration in worm and mouse optic nerve. Full-Text PDF Open Access
Source: Cell Reports
Language: English
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $5,620
OpenAlex ID: W4235470765