Year: 2019
Type: erratum
Abstract: In the original publication, Figure 4 and Figure 5 had incorrect images. The problem is that the corrected Figure 4 is missing in our manuscript, and Figure 5 and Figure 6 are the same images. The corrected Figure 4, Figure 5 and Figure 6 and their related legends are shown below. This erratum is published to correct that error. We apologize for this error. Propranolol inhibited HUVEC cell viability, migration, and promoted apoptosis via downregulation of miR-4295. HUVECs were treated with 15 μM of propranolol and transfected with miR-4295 mimic. A,B, The miR-4295 expression was detected using qRT-PCR. C, Cellviability, D, apoptosis and E, migration were respectively examined using CCK-8 assay, flow cytometry, and transwell assays. #Represents the data of propranolol group compared with the control group; #P < 0.05; ##P < 0.01; ###P < 0.001. *Represents the data in the propranolol + miR-4295 group compared with the propranolol + NC group; *P < 0.05; *P < 0.01; *P < 0.001. CCK-8, Cell Counting Kit-8; HUVECs, human umbilical vein endothelial cells; NC, negative control; qRT-PCR, quantitative reverse transcription-polymerase chain reaction Propranolol downregulated VEGF and VEGF-A expressions via downregulation of miR-4295. HUVECs were treated with 15 μM of propranolol and transfected with miR-4295 mimic. A, The mRNA expression and B, the concentration of VEGF were respectivelydetected using qRT-PCR and ELISA. C, The mRNA expression and D, the concentration of VEGF-A were respectively examined using qRT-PCR and ELISA. E, The protein level of VEGF and VEGF-A was assessed using Western blot assay. #Represents the data of propranolol group compared with the control group; #P < 0.05; #P < 0.01. *Represents the data in the propranolol + miR-4295 group compared with the propranolol + NC group; *P < 0.05; **P < 0.01. ELISA, enzyme-linked immunosorbent assay; HUVECs, human umbilical vein endothelial cells; mRNA, messenger RNA; miR-4295, microRNA-4295; NC, negative control; qRT-PCR, quantitative reverse transcription-polymerase chain reaction; VEGF, vascular endothelial growth factor Propranolol downregulated FLT1, FLT2, and FOXF1 expressions via downregulation of miR-4295.HUVECs were treated with 15 μM of propranolol and transfected with miR-4295 mimic. The mRNA expressions of A, FLT1, B, FLT2, and C, FOXF1 were detectedusing qRT-PCR. The protein level of D, FLT1, FLT2, and E, FOXF1 was assessed using Western blot assay. #Represents the data of propranolol group compared with the control group; #P < 0.05; #P < 0.01. *Represents the data in the propranolol + miR-4295 group compared with the propranolol + NC group; *P < 0.05. ELISA, enzyme-linked immunosorbent assay; HUVECs, human umbilical vein endothelial cells; mRNA, messenger RNA; miR-4295, microRNA-4295; NC, negative control; qRT-PCR, quantitative reverse transcription-polymerase chain reaction The correct figure order should be as follow:
Source: Journal of Cellular Biochemistry
DOI: 10.1002/jcb.28546
Language: French
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W4236741291