Work

Synthetic Shigella Vaccines: A Carbohydrate–Protein Conjugate with Totally Synthetic Hexadecasaccharide Haptens

Year: 1998

Type: article

Abstract: Advances in antibacterial glycoconjugate vaccines depend on the availability of defined fragments of the bacterial cell-surface polysaccharides. Oligosaccharide portions of the O-specific polysaccharide of the human pathogen Shigella dysenteriae type 1, have been assembled and attached to a human serum albumin (HSA; see below) to give semisynthetic vaccines that provide new directions against enteric diseases.

Source: Angewandte Chemie International Edition

DOI: 10.1002/(sici)1521-3773(19980202)37:1/2<138::aid-anie138>3.0.co;2-t

Author: Vince Pozsgay

Institutions: National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Language: English

Topic: Carbohydrate Chemistry and Synthesis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2030545676

FWCI: 4.853

Cites:

Cited by: 57

Related to: 10