Work

Dysbindin-1 and schizophrenia: from genetics to neuropathology

Year: 2004

Type: article

Abstract: The gene encoding dysbindin-1 has recently been implicated in susceptibility to schizophrenia. In this issue of the JCI, Talbot et al. show that, contrary to expectations, dysbindin-1 is located presynaptically in glutamatergic neurons and is reduced at these locations in schizophrenia. Further studies of dysbindin-1 and the proteins with which it interacts can be expected to throw light on the pathogenesis of schizophrenia.

Source: Journal of Clinical Investigation

DOI: 10.1172/jci200421470

Authors: Michael J. Owen, Nigel M. Williams, Michael C. O’Donovan

Institutions: Cardiff University, University of Wales

Language: English

Topic: Schizophrenia research and treatment

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W1999095609

FWCI: 2.296

Cites: 15

Cited by: 52

Related to: 10