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Crystal Structure of the C‐terminal Guanine Exchange Factor Module of Trio Reveals its Oncogenic Potential

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Year: 2019
Type: article
Source: The FASEB Journal
DOI: 10.1096/fasebj.2019.33.1_supplement.668.1
Authors: Sumit J. Bandekar, Nadia Arang, Ena S. Tully, Brittany A. Tang, Brenna L. Barton, Sheng Li, J. Silvio Gutkind, John J.G. Tesmer
Institutions: University of Michigan, University of California San Diego, Purdue University West Lafayette
Language: English

Topic: Protein Kinase Regulation and GTPase Signaling
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences, Argonne National Laboratory
Awards: G107546177, Interdepartmental Training in Pharmacological Sciences, Graduate Training in Cellular and Molecular Pharmacology, Structure, Function, and Inhibition of the RhoGEF Trio - a Target in Uveal Melanoma, G9000193054, G9000255730, G9000319824
OpenAlex ID: W4239973839
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Related to: 10
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