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Cover Picture: Probing Wavelength Regulation with an Engineered Rhodopsin Mimic and a C15-Retinal Analogue (ChemPlusChem 4/2012)

Year: 2012

Type: article

Abstract: The cover picture shows a short, C15-retinal analogue bound as an iminium to a lysine side chain from the crystal structure of reengineered CRABPII. The ‘caged’ chromophore represents an embedded and solvent-shielded C15-retinal analogue inside the protein cavity. The background stresses the human eye's ability to perceive a wide range of colors. This ability is in part mimicked in the designed protein system described in the Communication on page 273 ff. by J. H. Geiger, B. Borhan, and co-workers.

Source: ChemPlusChem

DOI: 10.1002/cplu.201290014

Authors: Kin Sing S. Lee, Tetyana Berbasova, Chrysoula Vasileiou, Xiaofei Jia, Wenjing Wang, Yoomi Choi, Farid Nossoni, James H. Geiger, Babak Borhan

Institution: Michigan State University

Language: English

Topic: Photoreceptor and optogenetics research

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W2023212836

FWCI:

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