Work

Familial Adenomatous Polyposis with Synchronous Invasive Colonic Carcinomas and Metastatic Jejunal Adenocarcinoma in a Nigerian Male

Year: 2010

Type: article

Abstract: Familial adenomatous polyposis is rare. Three cases were previously reported in Nigeria. An intriguing feature of this case is an ulcerated jejunal carcinoma which was metastatic rather than synchronous carcinoma. This patient presented with partial large bowel obstruction and the pathological analysis revealed 4 invasive adenocarcinomas, 3 in the colon and 1 in the jejunum (Dukes stage D). Palliative pancolectomy and jejunal tumour resection with chemotherapy was offered to him. He died eight months after surgery from disease progression. The challenges of managing a hereditary cancer syndrome in a resource poor country are highlighted.

Source: Rare Tumors

DOI: 10.4081/rt-2010-4-e66

Authors: Chukwuemeka C. Osuagwu, Okechukwu C. Okafor, Emmanuel R. Ezeome, Chrisogonus E. Uche, Charles Ememonu, Emeka Kesieme

Institutions: Imo State University Teaching Hospital, University of Nigeria Teaching Hospital

Language: English

Topic: Genetic factors in colorectal cancer

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,000