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Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice

Year: 2016

Type: article

Abstract: The genotype of the Nf1 mutant mice was incorrectly described.The correct text for Methods appears below.Mice and treatment procedures.Mx1-Cre;Nf1 tm1Par/tm1Tyj (referred to as Mx1-Cre;Nf1 flox/-) and control mice (Nf1 flox/+ ) were generated and treated with pIpC (Sigma-Aldrich) at 3-5 days, as described previously (16).

Source: Journal of Clinical Investigation

DOI: 10.1172/jci85325

Authors: Tiffany Chang, Kimberly Krisman, Emily Harding Theobald, Jin Xu, Jon Akutagawa, Jennifer O. Lauchle, Scott Kogan, Benjamin S. Braun, Kevin Shannon

Language: English

Topic: Neurofibromatosis and Schwannoma Cases

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4240631202

FWCI: 0.754

Cites:

Cited by: 6

Related to: 10