SHEA Guideline for Preventing Nosocomial Transmission of Multidrug-Resistant Strains ofStaphylococcus aureusandEnterococcus
Year: 2003
Type: letter
Abstract: Antibiotic-resistant pathogens constitute an impor-tant and growing threat to the public health. To under-stand how important they are, one must recognize that infectious diseases are in aggregate the leading cause of human death worldwide and the third leading cause of human death in the United States. More than 70 % of the bacteria that cause hospital-acquired infections are resis-tant to at least one of the drugs most commonly used to treat these infections.1 Antibiotic resistance occurs when a microbe acquires a gene, which allows the microbe to inactivate the antibiotic or otherwise nullify its antimicro-bial activity. This may occur as a spontaneous, genetic mutation or involve acquisition of a mobile genetic ele-ment such as a plasmid, transposon, integron, or gene cassette. It became obvious in the 1940s and 1950s that
DOI: 10.1086/502924
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4241768922
