Work

Do CH–Anion and Anion–π Interactions Alter the Mechanism of 2:1 Host–Guest Complexation in Arylethynyl Monourea Anion Receptors?

Year: 2017

Type: article

Abstract: Selective tuning of arylethynyl urea scaffolds for anionic guests requires an understanding of preferred binding motifs of the host-guest interaction. To investigate the binding preference of receptors without a pre-organized binding pocket, two electron-deficient phenylacetylene receptors with a single urea moiety have been prepared and were found to bind halides as 2:1 host-guest complexes that feature key CH-anion or anion-π interactions. These supporting interactions also appear to influence the mechanism of the 2:1 binding event.

Source: Chemistry - A European Journal

DOI: 10.1002/chem.201605452

Authors: Lisa M. Eytel, Annie K. Gilbert, Paul Görner, Lev N. Zakharov, Darren W. Johnson, Michael M. Haley

Institution: University of Oregon

Language: English

Topic: Supramolecular Chemistry and Complexes

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Science Foundation, National Institutes of Health, National Institute of General Medical Sciences, National Institute of Environmental Health Sciences

Awards: Reducing Susceptibility to Environmental Stress Throughout the Life Span, Design of Modular Receptors for Ion and Molecule Recognition