Year: 2003
Type: article
Abstract: ConclusionSo where do we stand today?We now appreciate that CX3CR1 and presumably fractalkine are important players in atherogenesis, and that CX3CR1 contains polymorphisms that modulate its adhesive and signaling functions and are associated with reduced risk of atherosclerotic cardiovascular disease.But to truly understand the mechanism of CX3CR1 and other genes in a highly complex and chronic disease process such as atherosclerosis, new practical intermediate markers are required in both experimental models and clinical studies.
DOI: 10.1172/jci18358
Author: Norman H. Bell
Institution: Medical University of South Carolina
Language: English
Topic: Bone Metabolism and Diseases
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W2064457971