Work

Improved Free‐Energy Landscape Quantification Illustrated with a Computationally Designed Protein–Ligand Interaction

Year: 2017

Type: article

Abstract: The front cover artwork is provided by the groups of David Baker (Univ. of Washington and HHMI) and Thomas Perkins (JILA, NIST and Univ. of Colorado). The image shows an AFM cantilever pulling on a computationally designed protein bound to digoxigenin attached to the end of a short DNA molecule with a conceptual free‐energy landscape as background. Read the full text of the article at 10.1002/cphc.201701147 .

Source: ChemPhysChem

DOI: 10.1002/cphc.201701340

Authors: William J. Van Patten, Robert Walder, Ayush Adhikari, Stephen R. Okoniewski, Rashmi Ravichandran, Christine E. Tinberg, David Baker, Thomas T. Perkins

Institutions: National Institute of Standards and Technology, Joint Institute for Laboratory Astrophysics, University of Colorado Boulder, Howard Hughes Medical Institute, University of Washington

Language: English

Topic: Force Microscopy Techniques and Applications

Subfield: Atomic and Molecular Physics, and Optics

Field: Physics and Astronomy

Domain: Physical Sciences

Open Access status: bronze

Funders: Howard Hughes Medical Institute, National Institutes of Health, National Institute of Standards and Technology, National Institute of General Medical Sciences

Award: Interdisciplinary Predoctoral Training in Molecular Biophysics

OpenAlex ID: W4242666679

FWCI:

Cites:

Cited by: 1

Related to: 10