Work

Mechanistic Study and Development of Catalytic Reactions of Sm(II)

Year: 2019

Type: article

Abstract: Despite the broad utility and application of SmI 2 in synthesis, the reagent is used in stoichiometric amounts and has a high molecular weight, resulting in a large amount of material being used for reactions requiring one or more equivalents of electrons. We report mechanistic studies on catalytic reactions of Sm(II) employing a terminal magnesium reductant and trimethyl silyl chloride in concert with a non-coordinating proton donor source. Reactions using this approach permitted reductions with as little as 1 mol% Sm. The mechanistic approach enabled catalysis employing HMPA as a ligand, facilitating the development of catalytic Sm(II) 5- exo - trig ketyl olefin cyclization reactions.

Source: Journal of the American Chemical Society

DOI: 10.1021/jacs.8b13119

Authors: Sandeepan Maity, Robert A. Flowers

Institution: Lehigh University

Language: English

Topic: Organometallic Complex Synthesis and Catalysis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Science Foundation, Division of Chemistry

Award: G7680511794