Year: 2005
Type: letter
Abstract: posed by the BCLC and by Marrero et al., 1 also precludes identification of factors predictive of survival or selection factors for optimal treatment if that therapy is not undertaken.In 2002, the AJCC/UICC adopted a simplified staging for HCC. 4 This staging was based on a detailed evaluation of tumor and liver factors associated with HCC.The study included patients from hepatobiliary centers in Japan, France, and the United States.5 More recently, this staging was independently validated in eastern and western patients undergoing resection for HCC.[6][7][8] We agree with Marrero et al. that the lack of a consensus on HCC staging hinders progress in critical areas of HCC research.However, given the heterogeneity of patients with HCC, a need remains for alternate stagings and treatment algorithms.
Source: Hepatology
DOI: 10.1002/hep.20863
Institution: University of Michigan
Language: English
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4243000347