Year: 2021
Type: article
Abstract: Of recent interest in neuromodulation is the use of Low Intensity Focused Ultrasound [1] (FUS), itself a topic of significant interest and of several experiments conducted recently in humans with FUS [2,3]. The FDA Guidance on acoustic output for diagnostic ultrasound limits the derated spatial-peak temporal-average ultrasound intensity (ISPTA.3) to 0.72 W/cm2. Much of the human neuromodulation work has been conducted at this limit [2]. However, as this threshold was established principally for diagnostic, as opposed to therapeutic ultrasound, some groups have conducted research at higher intensities [4], upwards of 6.16 W/cm2 to understand better what range of intensities is most effective for neurostimulation.
Source: Brain stimulation
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $3,310
OpenAlex ID: W3202055673