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Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency

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Year: 2021
Type: article
Source: Molecular Cell
DOI: 10.1016/j.molcel.2021.07.015
Authors: Ke Cong, Min Peng, Arne Nedergaard Kousholt, Wei Ting C. Lee, Silviana Lee, Sumeet Nayak, John Krais, Pamela S. VanderVere-Carozza, Katherine S. Pawelczak, Jennifer Calvo, Nicholas J. Panzarino, John J. Turchi, Neil Johnson, Jos Jonkers, Eli Rothenberg, Sharon B. Cantor
Language: English

Topic: PARP inhibition in cancer therapy
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: bronze

Funder: National Cancer Institute
Award: Novel DNA damage response therapeutics targeting replication protein A
OpenAlex ID: W4244798611
FWCI: 6.195
Cites:
Cited by: 132
Related to: 10
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