The selenium content of SEPP1 versus selenium requirements in vertebrates
Year: 2015
Type: article
Abstract: Selenoprotein P (SEPP1) distributes selenium (Se) throughout the body via the circulatory system. For vertebrates, the Se content of SEPP1 varies from 7 to 18 Se atoms depending on the species, but the reason for this variation remains unclear. Herein we provide evidence that vertebrate SEPP1 Sec content correlates positively with Se requirements. As the Se content of full length SEPP1 is genetically determined, this presents a unique case where a nutrient requirement can be predicted based on genomic sequence information.
Source: PeerJ
DOI: 10.7717/peerj.1244
Authors: Sam Penglase, Kristin Hamre, Ståle Ellingsen
Institution: University of Bergen
Language: English
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,395
OpenAlex ID: W1433941850