Perioperative Pembrolizumab or Pembrolizumab plus Enfortumab Vedotin (EV) and Cystectomy Compared to Cystectomy Alone in Patients With Muscle-Invasive Bladder Cancer (MIBC) Who Are Cisplatin-Ineligible (KEYNOTE-905/EV-303)
Year: 2020
Type: other
Abstract: Introduction & Objectives: Patients with MIBC who are ineligible for neoadjuvant cisplatin-based chemotherapy receive the standard of care treatment of radical cystectomy (RC) and pelvic lymph node dissection (PLND). This therapy alone is associated with high rates of recurrence and relatively poor overall survival (OS); novel perioperative systemic therapy regimens are needed. The
Author: Matthew Galsky
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4246828252