Work

Endocrine-Disrupting Chemicals in Human Fetal Growth

Year: 2020
Type: book-chapter
Abstract: Fetal growth is regulated by a complex interaction of maternal, placental, and fetal factors.The effects and outcomes that chemicals, widely distributed in the environment, may have on the health status of both the mother and the fetus are not yet well defined.Mainly mixtures of chemical substances are found in the mothers and placenta.Exposure to endocrine-disrupting chemicals (EDCs) can be associated with fetal growth retardation, thyroid dysfunction, and neurological disorders.EDCs mostly interfere with insulin, glucocorticoid, estrogenic, and thyroid pathways, with subsequent effects on normal endocrine and metabolic functions, which cause changes in the epigenome and state of inflammation with life-long effects and consequences.International scientific societies recommend the implementation of research and of all possible preventive measures.This review briefly summarizes all these aspects.
Language: English
Open Access status: bronze
OpenAlex ID: W4247310926
FWCI: 12.63
Cites: 67
Cited by: 35
Related to: 10