Role of Gomutra Haritaki With and Without Langhana and Pachana in the Management of Dyslipidemia: an Open Labelled Randomized Clinical Trial
Year: 2016
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Abstract: Dyslipidemia is primarily Santarpanajanya Vyadhi.So, Chikitsa aims towards Apatarpana Upakrama.Present clinical trial aimed to compare the clinical effect of Gomutra Haritaki with and without Langhana and Pachana in the management of Dyslipidemia.153 patients with abnormal lipid profile were selected and randomly divided in two Groups.In Group A, 76 patients were registered and 70 patients completed the treatment.In Group B, 77 patients were registered and 68 patients could complete the treatment.In Group A, Langhana in the form of one-time regular diet and Green gram soup was given for 4 days followed by 200 ml Dhanyaka Shunthi Siddha Jala twice daily for 10 days while in Group B, placebo capsules were given for initial 14 days.After 14 days of Langhana and Pachana or placebo treatment, Gomutra Haritaki, 2 tablets (500 mg each) thrice daily before meal for 8 weeks was administered in both Groups.Lipid profile was significantly reduced after Langhana and Pachana treatment in Group A while no change was found with placebo treatment in Group B. After completion of the treatment; in Group A, S. Cholesterol (8.59%), S. Triglyceride (8.72%), S.LDL (11.45%),S.VLDL (10.76%) reduced while in Group B, S. Cholesterol (9.51%), S. Triglyceride (7.91%), S.LDL (13.14%),S.VLDL (7.63%) decreased which was statistically significant.Langhana and Pachana with Dhanyaka Shunthi Siddha Jala is more effective to reduce fluctuate lipids like S. Triglyceride and S. VLDL.As Gomutra Haritaki is itself Dipana and Pachana drug, so it can reduce serum lipids significantly.However, Langhana and Pachana followed by Gomutra Haritaki is more effective in patients with poor liver and renal function.
Authors: Shivam Joshi, Mandip Goyal
Language: English
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4247658665