Work

Quorum sensing and biofilm formation in Streptococcal infections

Year: 2003

Type: review

Abstract: Members of the bacterial genus Streptococcus are responsible for causing a wide variety of infections in humans. Many Streptococci use quorum-sensing systems to regulate several physiological properties, including the ability to incorporate foreign DNA, tolerate acid, form biofilms, and become virulent. These quorum-sensing systems are primarily made of small soluble signal peptides that are detected by neighboring cells via a histidine kinase/response regulator pair.

Source: Journal of Clinical Investigation

DOI: 10.1172/jci20430

Authors: Dennis G. Cvitkovitch, Yung-Hua Li, Richard P. Ellen

Institution: University of Toronto

Language: English

Topic: Bacterial biofilms and quorum sensing

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: Canadian Institutes of Health Research, National Institute of Dental and Craniofacial Research

OpenAlex ID: W4247777507

FWCI: 1.204

Cites: 41

Cited by: 367

Related to: 10